Variant Assessment Scientist I: WGS - Development (REMOTE-US)

Company: Ambry Genetics
Location: Aliso Viejo
Posted on: March 28, 2025

Job Description:

Variant Assessment Scientist I: WGS - Development (REMOTE-US)Job Category: Genomic SciencesRequisition Number: VARIA003952Apply now

• Posted: February 5, 2025
• Full-Time
• RemoteLocationsShowing 1 locationRemote - USAAliso Viejo, CA 92656, USADescriptionCOMPENSATION: $95,000 to $105,000 per year. You are eligible for a Short-Term Incentive with the target at 5% of your annual earnings; terms and conditions apply.Variant Assessment Scientist I: WGS - Development (REMOTE-US)The primary responsibilities of this role include leading cross-functional projects to drive scientific innovation and excellence in variant classification, gene-disease validity, computational biology, and clinical data analytics. As a member of the Genomic Science Development team, the variant scientist will evaluate the latest scientific advancements to continuously improve the AmbryClassifi program and implement new analytical methods and automation tools. The successful candidate will focus on high impact data-driven outcomes to support business goals.Essential Functions:
  • Rigorous analysis of scientific data, evaluating external published literature and designing internal validation studies
  • Leadership of cross-functional groups at the team, department, and enterprise level
  • Demonstrate scientific expertise in molecular genetics, variant science, and gene-disease validity
  • Develop innovative technologies, software tools, AI/ML to improve the quality and efficiency of variant, gene, disease, and clinical data curation and classification
  • Develop robust processes to implement scientific advancements meeting all quality assurance standards and documentation requirements while maintaining operational efficiency
  • Develop educational training modules and methods to ensure broad adoption of all scientific advancements in a high-throughput laboratory environment
  • Other duties as assigned.Qualifications:
    • PhD, MD, or MS (with min. of 3 yrs experience) in scientific analysis and expertise in biological sciences, molecular genetics, human genetics, or related field
    • Thorough and ongoing knowledge of current theories and principles of human genetics
    • Whole Genome Sequencing experience
    • Excellent written, verbal, and interpersonal communication skills to engage stakeholders and socialize success
    • Ability to adapt to significant change that is inherent in development and innovation
    • Ability to work in and contribute to a fast-paced, highly collaborative environmentPreferred:
      • Post-doctoral fellowship or minimum +2 years of experience in clinical variant science preferred
      • Experience in project, program, and change management preferredAbout Us:Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster.At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community.At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes medical, dental, vision, FSA, paid sick leave and generous paid time off (PTO) program.The Company believes in second chance employment. Qualified applicants with arrest or conviction history will be considered regardless of their arrest or conviction history, consistent with local laws such as Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you. After making a conditional offer and running a background check, if the Company is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report.Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training.All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, sex, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of disability, protected medical condition as defined by applicable state or local law, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. If you have a disability or special need that requires accommodation, please contact us at careers@ambrygen.com.
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Keywords: Ambry Genetics, Aliso Viejo , Variant Assessment Scientist I: WGS - Development (REMOTE-US), Other , Aliso Viejo, California